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Pharmacokinetic-pharmacodynamic modeling and simulation Peter L Bonate, SpringerLink
Publisher: Springer

Part of these questions may be addressed through simulations from pharmacokinetic (PK) and pharmacodynamic (PD) models of HU. Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. Learn How to Build Automated Traffic Machines. Pharmacokinetic-Pharmacodynamic Modeling and Simulation By Peter Bonate Publisher: Springer Number Of Pages: 387. Pharmacokinetic-Pharmacodynamic Modeling and Simulation, Pharmacokinetic-Pharmacodynamic Modeling and Simulationby Peter L. One of the authoritative texts on the subject. Model simulations were performed with the finalized model to understand the effect of formulation on corneal and retinal pharmacokinetics after periocular administration. Title:Pharmacokinetic-Pharmacodynamic Modeling and Simulation Author:Peter L. Celecoxib kinetics in the BN rat cornea can be described by a two- compartment (periocular space and 2001;239:850–858. Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Pharmacokinetic-pharmacodynamic modeling and simulation. Additionally, the company's new additions to the pharmacokinetic, pharmacodynamic, modeling, and simulation services area are Dr. A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. Nidal Al-Hunti, principal scientist; Dr. The Art of Modeling: Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Robert Bauer, vice president of pharmacometrics; Dr. A comprehensive simulation study to assess the utility of a stage-specific pharmacokinetic-pharmacodynamic (PK-PD) model for predicting within-host parasite response was performed. A companion website includes the full text online, plus interactive simulations for student practice using different pharmacokinetic/pharmacodynamic models and parameters. Bonate Publisher:Springer ISBN:139939399X ISBN33: Date3116-31-31. Bonate, "Pharmacokinetic-Pharmacodynamic Modeling and Simulation" Sp ger | 2011 | ISBN: 144199484X | 651 pages | PDF | 11,1 MB.